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Given that the IC 100 concentration of niclosamide required to completely prevent viral replication in SARS-CoV-2 infected Calu-3 lung cells as measured by Ko et al (34) as 2M, a 20uM niclosamide solution nasal spray is 10x this IC 100

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doi: 10.1038/s41568-022-00537-3 39

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Using dansylation and benzyolation as model systems, we demonstrated that high-quality MS/MS spectrum prediction could be achieved using a small-sized training set of variable CDMs

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